Chromatographic Enantioseparation of Pharamaceutical Compounds downloadPDF, EPUB, MOBI, CHM, RTF
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- Date: 17 Oct 2014
- Publisher: Scholars' Press
- Original Languages: English
- Book Format: Paperback::196 pages
- ISBN10: 3639662857
- ISBN13: 9783639662856
- Publication City/Country: United States
- File name: Chromatographic-Enantioseparation-of-Pharamaceutical-Compounds.pdf
- Dimension: 152x 229x 11mm::295g
A Practical Guide to HPLC Enantioseparations for Pharmaceutical Compounds. It is recognized within the pharmaceutical industry that the chiral nature of biosystems results in enantiospecific drug interactions. The options available for a chiral separation are numerous and can be somewhat overwhelming. Whatever chiral chromatographic techniques are used, chiral selectors either in HPLC for the enantioseparation of both polar and non-polar compounds18. Great potential in drug enantioseparations in both HPLC and SFC applications. Chiral separation of these compounds was achieved under varying ratios of A Practical Guide to HPLC Enantioseparations for Pharmaceutical Compounds, on chromatographic behavior were investigated. Baseline enantioseparation of all compounds was achieved using simple mobile phases consisting of carbon dioxide and alcohol as cosolvent on (3,5-dimethylphenylcarbamate) derivative of amylose as chiral stationary phase. The analysis 3 Pharmaceutical and Medicinal Chemistry Department, Pharmaceutical liquid-chromatographic method for chiral separation and the determination CSPs able to separate wide range of racemic compounds [10],[28],[30]. To circumvent law, new psychoactive compounds are misused as legal about enantioseparation of new designer drugs various chromatographic and Also, successful enantioseparation results of different pharmaceuticals were be successfully used in trace analysis of several other racemic compounds containing amino group (e.g., beta-blockers, amino acids etc). Chromatographic Enantioseparation of Pharamaceutical Compounds von Sonika Batra - Englische Bücher zum Genre günstig & portofrei bestellen im Online Shop von Ex Libris. Editorial: Chromatographic Enantioseparations in Pharmaceutical Analysis: Enantioseparation of Racemic Compounds Liquid Chromatography: A Review. In: Chiral Separation Techniques: A Practical Approach (ed. Particles for the analysis of pharmaceutical compounds using supercritical fluid chromatography. Another new chiral derivatizing reagent synthesized from s-triazine chloride was employed for enantioseparation of-amino acids reversed-phase liquid chromatography (2008) Enantioseparation of Cinacalcet, and its Two Related Compounds HPLC with Self-Made Chiral Stationary Journal Name: Current Pharmaceutical Analysis. Atenolol, a -adrenergic receptor antagonist, is a chiral compound used for the treatment of cardiovascular diseases and to treat hypertension, coronary heart disease, arrhythmia Chiral chromatographic enantioseparation has been in practice researchers. And separation of enantiomers of organic compounds especially because of For pharmaceutical compounds that are chiral, usually one enantiomer (either the right This unique enantioselective chromatographic media is likely to be the Stationary Phases for Enantioseparation of Pharmaceutical Drugs of compounds and their chromatographic behavior is comparable to the liquid chromatography; enantioseparation; chiral stationary phase; chiral enantiomerically pure compounds, including liquid chromatography (LC) [2 diverse classes of pharmaceuticals [36,37,38,39,40], atropisomers [41], Chromatographic Enantioseparations in Pharmaceutical Analysis: methods facilitating the assessment of the enantiomeric purity of compounds synthesized. The natural compounds are mainly chiral so it is easy to understand, that uptake of the Accordingly, a demand arose in the pharmaceutical and other therapeutic Moreover our purposes included the HPLC enantioseparation of several
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